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Description

Melatoning Cream 2% is a skin-brightening topical cream combining Melatonin — an endogenous neurohormone and potent antioxidant that modulates melanocyte stimulating hormone (MSH) receptor activity and scavenges reactive oxygen species that upregulate melanogenesis — and Niacinamide, which inhibits melanosome transfer from melanocytes to keratinocytes via suppression of PAR-2 receptor signaling. The dual-mechanism formulation addresses both melanin production and distribution, suitable for all skin types including sensitive skin. Indicated for melasma, solar lentigines, post-inflammatory hyperpigmentation, and diffuse uneven skin tone.

Indication

Designed for routines targeting the visible appearance of hyperpigmentation, localized dark spots, and uneven skin tone within structured daily skin-care programs.

Packaging

Supplied as a 30 g tube per unit, as stated in the product specification.

Protocol

Apply a pea-sized amount to clean, dry skin twice daily (morning and evening), massaging until fully absorbed; apply broad-spectrum SPF 30+ as the final morning step to prevent UV-induced melanogenesis counteracting treatment efficacy. Allow 8–12 weeks of consistent daily use for clinical assessment of depigmenting response. Avoid simultaneous use with products containing high-concentration retinoids or exfoliating acids without clinician guidance.

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